Pharmacological action – beta-adrenomimetic, bronchodilating.
Indications
bronchial asthma:
– relief of attacks of bronchial asthma, incl. with exacerbation of severe bronchial asthma;
– prevention of attacks of bronchospasm associated with exposure to an allergen or caused by physical activity;
– use as one of the components in long-term maintenance therapy of bronchial asthma;
COPD with reversible airway obstruction;
Chronical bronchitis.
Contraindications
hypersensitivity to any component of the drug;
management of preterm birth;
threatened abortion;
children’s age up to 2 years.
With caution: tachyarrhythmia, myocarditis, heart defects, aortic stenosis, ischemic heart disease, severe chronic heart failure, arterial hypertension, thyrotoxicosis, pheochromocytoma, decompensated diabetes mellitus, glaucoma, epileptic seizures, renal or hepatic insufficiency, simultaneous use of non-selective β-blockers, pregnancy, period lactation.
Use during pregnancy and lactation
For pregnant women, the drug is prescribed only if the expected benefit to the patient outweighs the potential risk to the fetus.
During post-registration surveillance, rare cases of various malformations in children, including the formation of the cleft palate and malformations of the limbs, were identified against the background of mothers taking salbutamol during pregnancy. In some of these cases, mothers took multiple concomitant medications during pregnancy. A causal relationship with the drug has not been established.
Salbutamol is likely to pass into breast milk, so it is not recommended to prescribe it to lactating women, unless the expected benefit to the patient outweighs the potential risk to the child. There is no data on whether salbutamol present in breast milk has a harmful effect on the newborn.
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